Elenco pubblicazioni

1. De Caro C, Leo A, Nesci V, Ghelardini C, di Cesare Mannelli L, Striano P, Avagliano C,
Calignano A, Mainardi P, Constanti A, Citraro R, De Sarro G, Russo E. Intestinal
inflammation increases convulsant activity and reduces antiepileptic drug efficacy in a
mouse model of epilepsy. Sci Rep. 2019 Sep 27;9(1):13983
2. Iannone LF, Preda A, Blottière HM, Clarke G, Albani D, Belcastro V, Carotenuto M,
Cattaneo A, Citraro R, Ferraris C, Ronchi F, Luongo G, Santocchi E, Guiducci L, Baldelli P,
Iannetti P, Pedersen S, Petretto A, Provasi S, Selmer K, Spalice A, Tagliabue A, Verrotti
A, Segata N, Zimmermann J, Minetti C, Mainardi P, Giordano C, Sisodiya S, Zara F,
Russo E, Striano P. Microbiota-gut brain axis involvement in neuropsychiatric
disorders. Expert Rev Neurother. 2019Oct;19(10):1037-1050.
3. P.Mainardi, P.Carta, P.Striano. How Knowledge on Microbiota may be Helpful to
Establish an Optimal Diet for Health Maintenance. Int J Nutrition, 2018.
4. Mainardi P, Carta P, Montinari M, Striano P et al. From the Ancient Diets to the Recent
Acquisitions on the Role of Brain Inflammation in Epilepsy, Are there Any Links? J
Neurol Neurophysiol 2015, 6:3
5. Errichiello L, Pezzella M, Santulli L, Striano S, Zara F, Minetti C, Mainardi P, Striano P.
A proof-of-concept trial of the whey protein alfa-lactalbumin in chronic cortical
myoclonus. Mov Disord. 2011 Dec;26(14):2573-5
6. Russo E, Scicchitano F, Citraro R, Aiello R, Camastra C, Mainardi P, Chimirri S, Perucca
E, Donato G, De Sarro G. Protective activity of α-lactoalbumin (ALAC), a whey protein
rich in tryptophan, in rodent models of epileptogenesis. Neuroscience. 2012 Dec
13;226:282-8.
7. Citraro R, Scicchitano F, De Fazio S, Raggio R, Mainardi P, Perucca E, De Sarro G, Russo
E. Preclinical activity profile of α-lactoalbumin, a whey protein rich in tryptophan, in
rodent models of seizures and epilepsy. Epilepsy Res. 2011 Jun;95(1-2):60-9.
8. Striano P, D'Amato E, Pezzella M, Mainardi P, Zara F, Striano S. Sudden death in
Unverricht-Lundborg patients: is serotonin the key? Neurol Sci. 2010 Feb;31(1):115-6
9. Mainardi P, Leonardi A, Albano C. Potentiation of brain serotonin activity may inhibit
seizures, especially in drug-resistant epilepsy. Med Hypotheses. 2008;70(4):876-9.
10. Mainardi P, Albano C. Is the antiepileptic effect of the ketogenic diet due to ketones?
Med Hypotheses. 2008;70(3):536-9.
11. Albano C, Cupello A, Mainardi P, Scarrone S, Favale E. Successful treatment of epilepsy
with serotonin reuptake inhibitors: proposed mechanism. Neurochem Res. 2006
Apr;31(4):509-14.
12. Luccardini C, Barilà B, Cupello A, Robello M, Mainardi P. Regulation of the expression
of low affinity GABAA receptors in rat cerebellar granule cells. Amino Acids.
2001;21(2):119-28.

13. Cupello A, Mainardi P, Robello M, Thellung S. Effect of nitric oxide donors on GABA
uptake by rat brain synaptosomes. Neurochem Res. 1997 Dec;22(12):1517-21.
14. Lunardi G, Mainardi P, Rubino V, Fracassi M, Pioli F, Cultrera S, Albano C. Tryptophan
and epilepsy. Adv Exp Med Biol. 1996;398:101-2.
15. Favale E, Rubino V, Mainardi P, Lunardi G, Albano C. Anticonvulsant effect of
fluoxetine in humans. Neurology. 1995 Oct;45(10):1926-7.
16. Loeb C, Mainardi P, Besio G, Lunardi G, Cogliolo I, Pioli F. Plasma and CSF amino acid
levels in ALS. Acta Neurol Scand. 1994 Sep;90(3):223-4.
17. Loeb C, Patrone A, Besio G, Balestrino M, Mainardi P. The antiepileptic effect of low-
dose amino-phosphono-valeric acid (APV) is not enhanced by phosphatidylserine
association. Seizure. 1993 Dec;2(4):309-10.
18. Cupello A, Gasparetto B, Mainardi P, Vignolo L, Robello M. Effect of protein kinase C
activators on the uptake of GABA by rat brain synaptosomes. Int J Neurosci. 1993 Mar-
Apr;69(1-4):131-6.
19. Benassi E, Besio G, Cupello A, Mainardi P, Patrone A, Rapallino MV, Vignolo L, Loeb
CW. Evaluation of the mechanisms by which gamma-amino-butyric acid in association
with phosphatidylserine exerts an antiepileptic effect in the rat. Neurochem Res. 1992
Dec;17(12):1229-33.
20. Vignolo L, Cupello A, Mainardi P, Rapallino MV, Patrone A, Loeb C. Accumulation of
labeled gamma-aminobutyric acid into rat brain and brain synaptosomes after i.p.
injection. Neurochem Res. 1992 Feb;17(2):193-9.
21. Cupello A, Rapallino MV, Mainardi P. Components of basal and GABA activated 36Cl-
influx in rat cerebral cortex microsacs. Int J Neurosci. 1992 Jan;62(1-2):35-43.
22. Loeb C, Patrone A, Besio G, Balestrino M, Mainardi P. The excitatory amino acid
antagonist amino-phosphono-valeric acid (APV) provides protection against penicillin-
induced epileptic activity in the rat. Epilepsy Res. 1990Aug;6(3):249-51.
23. Rapallino MV, Cupello A, Mainardi P, Besio G, Loeb CW. Effect of phosphatidylserine
on the basal and GABA-activated Cl- permeation across single nerve membranes from
rabbit Deiters' neurons. Neurochem Res. 1990 Jun;15(6):593-6.
24. Rolandi R, Robello M, Mao C, Mainardi P, Besio G. Adsorption of gamma-aminobutyric
acid to phosphatidylserine membranes. Cell Biophys. 1990 Jan-Apr;16(1-2):71-83
25. Loeb C, Marinari UM, Benassi E, Besio G, Cottalasso D, Cupello A, Maffini M, Mainardi
P, Pronzato MA, Scotto PA. Phosphatidylserine increases in vivo the synaptosomal
uptake of exogenous GABA in rats. Exp Neurol. 1988 Feb;99(2):440-6.
26. Benassi E, Besio G, Bo GP, Cocito L, Maffini M, Mainardi P, Morselli PL, Loeb C.
Preliminary observations on the activity of progabide, administered as monotherapy in
complex partial seizures. Int J Clin Pharmacol Res. 1988;8(5):353-61.

27. Cupello A, Besio G, Mainardi P. A method for the determination of the integrity of
labeled GABA used in membrane receptor binding assay. Neurochem Res. 1987
Mar;12(3):311-3.
28. Cupello A, Rapallino MV, Besio G, Mainardi P. An electrophoretic method for the
determination of the proportion of gamma-aminobutyric acid in a mixture of labeled
neurotransmitter and its catabolites. Anal Biochem. 1987 Jan;160(1):14-6.
29. Bo GP, Mainardi P, Benassi E, Besio G, Faverio A, Scotto PA, Loeb C. Parenteral
penicillin model of epilepsy in the rat: a reappraisal. Methods Find Exp Clin Pharmacol.
1986 Aug;8(8):491-6.
30. Loeb C, Besio G, Mainardi P, Scotto P, Benassi E, Bo GP. Liposome-entrapped gamma-
aminobutyric acid inhibits isoniazid-induced epileptogenic activity in rats. Epilepsia.
1986 Mar-Apr;27(2):98-102. PubMed PMID: 3956456.
31. Loeb C, Bo GP, Scotto PA, Benassi E, Besio G, Mainardi P, Faverio A. GABA and
phospholipids in penicillin-induced seizures. Exp Neurol. 1985 Oct;90(1):278-80.
32. Mancardi GL, Schenone A, Tabaton M, Tassinari T, Mainardi P. Polyglucosan bodies in
the sural nerve of a diabetic patient with polyneuropathy. Acta Neuropathol.
1985;66(1):83-6.